Thursday, 2 June 2022

The Mutant Genes in the Early Onset Familial Alzheimer's – Part 1 - Alzheimer's 6

Previously, I posted about chromosomes related to the Alzheimer's disease and gene mutations as the genetic marker that believe to lead to this pathological disease.



Image 1- Simple talks of Alzheimer's patients


You may read previous postings (Part 1 and Part 2):

As we might know that the progressive declined in cognitive functions in Alzheimer's disease are associated with depositions of aggregated protein in form of extracellular plaques and neurofibrillary tangles in the brain.



Image 2- Plants, just for illustration



Image 3- Dialogs of normal and Alzheimer’s person.

Early-onset Alzheimer's disease appears about in the thirties and mid-sixties of the age which are characterized by the mutation of single gene in any chromosome in chromosome 1, chromosome 14 and chromosome 21.

Long investigations about the mutant gene that causes abundance of amyloid plaques were conducted.

Then the scientists found that this gene, the gene encoding amyloid precursor protein (APP), sits in chromosome 21.

It's an autosomal dominant.

# To be continued to Part 2

## Previous postings:

8 comments:

  1. Una enfermedad que nadie quisiera tener , pues si los recuerdos se olvidan es como si no hubieran existido . Un abrazo y feliz fin de semana.

    ReplyDelete
  2. Siempre es interesante pasar a leerte. Un abrazo.

    ReplyDelete
    Replies
    1. Thanks to visit my blog-
      The Mutant Genes in the Early Onset Familial Alzheimer's – Part 1 - Alzheimer's 6
      -
      Previously, I posted about chromosomes related to the Alzheimer's disease and gene mutations as the genetic marker that believe to lead to this pathological disease.

      Delete
  3. This is an interesting post.
    Have a nice weekend.

    ReplyDelete
  4. No tengo antecedentes familiares pero aún así me da miedo pensar en ella.

    Saludos.

    ReplyDelete
    Replies
    1. Thanks to visit my blog-
      The Mutant Genes in the Early Onset Familial Alzheimer's – Part 1 - Alzheimer's 6
      -
      Image 1- Simple talks of Alzheimer's patients

      You may read previous postings (Part 1 and Part 2):
      - In what chromosomes are the gene mutation related to Alzheimer's Disease? - Part 1 - Alzheimer's 5
      - In what chromosomes are the gene mutation related to Alzheimer's Disease? - Part 2 - Alzheimer's 5

      As we might know that the progressive declined in cognitive functions in Alzheimer's disease are associated with depositions of aggregated protein in form of extracellular plaques and neurofibrillary tangles in the brain.

      Delete
  5. Esta doença é terrível! Obrigada pela publicação!
    .
    Não quero o silêncio nem a solidão...

    Beijos e um bom fim de semana.

    ReplyDelete
  6. Senile dementia causes similar behaviors...
    All the best for you, Rainbow.
    ~~~~~~

    ReplyDelete

The White Spider Lily at our City Garden – Nature 36

When we visit our city garden about few weeks ago, surprisingly we saw white spider lily at the corner of garden for the first time. Image 1...