What is Knockout Animals ? - Part 1- Science 8

Knockout mice, credit to National Human Genome Research Institute

We might confuse with these two terms:

- knockout
- Transgenic.

Transgenic is insertion of exogenous DNA into random non homologous site in the animal genome.

While Knockout is insertion of modified DNA at a specific homologous site in the animal genome.

It is interesting to discuss about knockout term furthermore in this posting.

In addition, knockout is the word commonly used to inactive an exist of specific gene in particular organism.

The way to knocked out is by replacing or disrupting the target gene with an artificial piece of DNA.

This is a genetic technique by using homologous recombination to change an endogenous gene.

Garden corner, just illustration

Then, targeted gene could be permanent or conditional inactive or knockout.

Knockout could cause alter phenotype of organisms.

The changes might include behavior, appearance (observable physical) and biochemical characteristics of organisms.

Then, knockout organisms are used in learning about a gene that has been sequenced, which incompletely known function.

# To be continued to Part 2

# Previous postings:

- The Rainbow Before Evening : Making Perfume in the Organic Chemistry Laboratory - Science 1
- The Rainbow Before Evening : Russian Covid 19 Vaccine Advantages – Science 2

Outlawed - An Epic Western Novel – Part 1 - Reading 4

Cover of Outlawed, a Western fiction

Outlawed is a Western fiction by Anna North.

The writer grown up in Los Angeles and lives in Brooklyn. She was a graduate of Iowa Writer’s Workshop.

Ada is the protagonist in this book. The story is set in the late of nineteenth century.

From the front jacket of this book, “In the year of our Lord 1894, I became an outlaw. Like a lot of things, it didn’t happen all at once.”

The story begins when Ada feels lucky to get married with a handsome boy from the good family.

Ada’s mother is a midwife and Ada always happy to help her mother doing her job.

Like other her peers, she married at seventeen, and she loves her husband.

Their duty is to have children for baby Jesus since God sent the Great Flu (flu pandemic) to cleanse the world of evil.

Several months after they wed, Ada’s womb is still empty. Meanwhile in her town, the barren women are routinely hanged as witches.

# To be continued to Part 2

## Previous posting:

- Family Saga and Meaning to be a Good Person – Part 1 - Reading 1
- Family Saga and Meaning to be a Good Person – Part 2 - Reading 1

When should I get the Botox Cosmetic? - Part 2 – Healthy Life 16

The smile of camels (Credit: Fayez Nureldine/AFP/Getty Images).

Previous posting:

- When should I get the Botox Cosmetic? - Part 1 – Healthy Life 16

Do you think someone has bad reputation or cheat on you whenever she get Botox injection in her forehead or her face?

Finally I found it out.

It was said, “If Botox purpose to get $55 million dollar contest the most beauty camel in King Abdulaziz Camel Festival, forget it!!!”

The Botox injection into camels like a cheat in this contest.

I'm not going to cheat anyone, even with my face.

I'm thinking about a prevention, before the frown lines or “eleven” lines between my eyebrows are exist in my forehead, so that I will not look:

- angry
- tired
- or unhappy.

Trees nearby jogging track.

One of medical practitioners said that if you think that you have inherit the early frown lines or wrinkles, do not wait the wrinkle create the lines.

So in this case, Botox treatment is the best under 30 year old, because Botox is not a filler. Botox works to paralyze muscles and need to be repeated.

What do you think, do you think in age before 30 year-old is too early to get Botox Cosmetic?

Or just wait until the lines between the eyebrows and forehead are appearing?

# Previous postings:

- Measles Outbreak in a Recent year – Part 1 – Healthy Life 11
- Measles Outbreak in a Recent year – Part 2 – Healthy Life 11
- Do you know about E. coli Bacteria? - part 1 - Healthy Life 12
- Do you know about E. coli Bacteria? - part 2 - Healthy Life 12

The Surprising Fact - Cooked Shrimps are Cheaper than Raw Ones – Part 2 - Food 8

Plastic bags of seafood market and deli

Previous post (part 1):

- The Surprising Fact - Cooked Shrimps are Cheaper than Raw Ones – Part 1 - Food 8

When I was in the market, I saw both the raw and cooked shrimps.

The shrimps either plain cooked or cooked with recipes, Louisiana special cuisine.

Off course!

What surprising me was the price, you may compare them:

- cooked shrimps are US$ 9.99 per pound
- whereas raw ones are US$ 11.99 per pound.

Cooked shrimps are two dollar cheaper than raw ones.

Why?

I really don’t know the exact or true answer, what happen behind the prices, honestly.

However, I guess there are several factors caused cooked shrimp cheaper than raw or fresh ones.

Cooked shrimps

Here they are the answers:

1) about to expire or go bad

- the sellers want to get rid of it as soon as possible.

2) smaller size

- bigger size is expensive

I decided to buy cooked shrimps together with boiled corn. Ready to go and to eat.

Make me wonder, did you find in your place where cooked things are cheaper than raw ones?

# Previous posting:

- The Rainbow Before Evening : Green Bean and Papaya Delight – Food 4
- The Rainbow Before Evening : The Best Steakhouse in my City, Louisiana – Food 5
- The Rainbow Before Evening : Have You Tasted Matcha Latte with Soy Milk or Almond Milk? - Food 6

When should I get the Botox Cosmetic? - Part 1 – Healthy Life 16

Botox Cosmetic Injections (Credit: Noravector/123rf.com)

Every time I get out from my house, I always pass the nice building with big signs of the professional names in the medical fields, the services, and the treatments.

The building is located at the intersect of a quite drive and a busy traffics with 5 traffic lines.

The nice building looks not so busy among the:

- restaurants
- bakery
- and sandwich fast food.

Because the parking lot is in rear of the building, the clients get in and out with the good manners through the quite drive.

There is a Cosmetic Center that serves vary of treatments, including cosmetic surgeries, hair loss replacement, and medical spa.

Then?

Cup cakes, just illustration.

The services are all what we need to treat and fix in our hair, eyes, face, body, breast, and skin.

The building is okay, nothing wrong. The led signs are still blinking with the facilities and services. I knew that this Cosmetic Center is the first Botox Cosmetic in my state.

Lately, I just have an imagination about one of their services, Botox, and the smile of camels.

Sounds good to me, Botox Cosmetic for the human beauty. I just wondered about the beauty of camel last year. How come camels got Botox Cosmetic and had a negative reputations.

# To be continued to Part 2

The Surprising Fact - Cooked Shrimps are Cheaper than Raw Ones – Part 1 - Food 8

Cooked shrimps and boiled corns

We went to Tony’s seafood market and deli, the biggest seafood market in my city, Baton Rouge, Louisiana, this morning.

We planned to buy one or two pounds of shrimps to cook with a recipe which I found in a blog.

The recipe is quite simple, but I think attractive to try it.

Just to let you know that Louisiana has several kinds of shrimps. Four commercial values are:

- white shrimp (Litopenaeus setiferus)
- brown shrimp (Farfantepenaeus aztecus)
- seabob shrimp (Penaeus sp)
- pink shrimp (Farfantepenaeus duorarum)

Louisiana produces around 100 million pounds of all kind shrimps per year, mainly from the Gulf of Mexico.

The gulf, actually belongs to both Mexico and USA.

Another kind of cooked shrimp

The shrimp industries provided 15 thousand jobs and greatly impact on Louisiana economic.

Yes, fishing and agriculture industries are important to Louisiana, and many southern states of USA.

They bring about US$ 1.3 billion annually to Louisiana state.

# To be continued to Part 2

## Previous postings:

- A Tropical Plant Called Pineapple – Food 1
- Oyster is One of Favorite Seafood in Louisiana – Food 2
- Do You Know about Golden Kiwis Fruit? - Food 3

Traditional Books versus Electronic Books for Children – Part 2 – Reading 3

Books for children sold out

Better to read previous post (part 1):

- Traditional Books versus Electronic Books for Children – Part 1 – Reading 3

It is because reading book able to support their healthy brain development, and important for development of:

- vocabulary
- literacy
- language skill
- then lead to better academic.

Many “busy” parents give tablet or any screen for their children with many books in it, depending to kind of tablets.

Some of interactive e-books can help parents to read the books when busy parents do not have time to read them for their children.

Few other parents give time limit for their kids to access electronic devices, and facilitate them with traditional books.

Wild fruit for birds, just for illustration.

Ms Lynnell is one of them, she always has time for reading the traditional books for Cassie. Cassie' parents also have some times for her bed time reading.

Cassie loves to show all of hers. She like to show her baby dolls, puzzles, and books.

She prefers traditional books because she can show, carry, and pretend to read her books for every body.

She has favorite pages in every single book. Oh-oh she drawn happy faces and little dolls on those pages too.

Finally, what do you think about traditional and e-books?

# Previous postings:

- Family Saga and Meaning to be a Good Person – Part 1 - Reading 1
- Family Saga and Meaning to be a Good Person – Part 2 - Reading 1
- Like Crazy, “a wild child cares for the wild woman who raised him” - Reading 2